A protein structure popping out of clusters of data
MIDS Capstone Project Fall 2021

S2-ProCLAIM

S2-PROCLAIM (Structurally Similar Protein Clustering AI model) empowers scientists to navigate a brand new, historically significant dataset of 3D protein structures by AlphaFold2. AlphaFold2 is an AI model by DeepMind that led to a recent scientific breakthrough in protein 3D structure predictions in 2020, and its data was released to the public in July 2021. S2-PROCLAIM clusters proteins by their 3D structural similarity, which has a high correlation with the proteins' molecular functions. Using the MVP, the scientists can quickly search and identify a group of similar proteins and discover previously unknown relationships. In turn, the search results will inform the creation of new hypotheses in the fields of life sciences, food science, manufacturing, and more. (Research paper in review.)

A protein structure popping out of clusters of data
S2-ProCLAIM clusters AlphaFold2 structures using novel embeddings

Video

S2-ProCLAIM - Demo

S2-ProCLAIM - Demo

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Last updated:

January 16, 2022